PhD position- DinoPlast

The HEAL group is recruiting a PhD position to the project "DinoPlast", under codirection with Thomas Lacour (Phytox, IFREMER Nantes). In a warming world ocean, identifying the molecular effectors of algal primary production is increasingly important for understanding global carbon cycle processes. Dinoflagellates are by far the least understood group of algae from a molecular point of view. They play complex and important roles as phototrophs, mixotrophs, coral symbionts and agents responsible for harmful algal blooms (HABs), but for which there are historically no feasible experimental models. DinoPlast seeks to build metabolic networks for four dinoflagellate species (Amphidinium, Lepidodinium, Karlodinium and Lingualax) as molecular models of the processes that support the dinoflagellate chloroplast, bridging complementary views of translational profiling and physiology with global ocean ecosystems. Key objectives include establishing RiboSeq as a quantification of gene expression for all four species; assessing changes in the expression of plastid-associated metabolism in each species across…

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PanArctica

Work in the HEAL group is supported by an ANR JCJC, “PanArctica” (Projet-ANR-21-CE02-0014), awarded 2021-2025.The Arctic Ocean is set apart from all other oceans due to being encircled by land, its extreme environment, and its distinct ecosystem, characterised by strong seasonal succession. Anthropogenic climate change is rapidly changing the Arctic Ocean into a warmer, fresher habitat, and understanding the biological communities that support the Arctic is urgent for projecting its future robustness.The data obtained from this project will provide in-depth insights into the functional biology of an important and rapidly changing oceanic habitat. In the long term, these may allow more refined understanding of which species will proliferate in the future Arctic Ocean. In addition, proteins identified that confer temperature, salinity and photo-tolerance in Arctic native species may be explored as candidates for improving the productivity and robustness of biofuels and other cultivable crop species. 

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The Haptophyte Pan-Genome

Work in the HEAL Group is supported by a JGI Community Sequencing Programme grant, "the Haptophyte Pan-Genome", awarded 2022."The Haptophyte Genome Project" aims to expand the phylogenetic breadth of sequenced Haptophyte genomes, particularly freshwater samples. The Haptophytes are an ancient and complex lineage of eukaryotic algae of immense ecological importance, forming the second most significant contribution to planetary eukaryotic photosynthesis after diatoms [1, 2]. Sequencing genomes and transcriptomes of phylogenetically diverse haptophytes and relevant outgroups will address long-standing questions pertaining to: 1) the phylogenetic framework and genomic diversity of species selected from freshwater, salty continental and marine environments, 2) the transition of haptophytes between marine and freshwater systems, 3) the phylogenetic composition of the haptophyte genome with particular regard to its chloroplast, 4) key components involved in biomineralization, alkenone biosynthesis, and toxin production, 5) cellular machinery associated with mixotrophy, and 6) prevalence of pan-genomes, relevant to a heating ocean. 

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Biolit Mission

The HEAL group was pleased to participate in the Biolit mission https://biolit.fr/ for the International Day of Global Biodiversity on May 24, 2025. BioLit is a participatory science program on coastal biodiversity, created and supported by Planète Mer. It is run under the scientific responsibility of the Dinard marine station of the Museum National d'Histoire Naturelle (MNHN). It enables everyone to take action to better understand and preserve the biodiversity of the seaside. We spent a day counting algal and mollusc species at the épave de l'OTAN at Octeville, Normandie, France. The best part of the day was apparently the beer at the end :-)

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LeDNA mission

The HEAL group was pleased to participate in the LeDNA mission, organized for the International Day of Global Biodiversity on May 22, 2024 https://environmental-dna.ethz.ch/research/ercledna/global-lake-sampling.html. The global loss and redistribution of biodiversity is a hallmark of the Anthropocene. Our challenge is to generate information about how altered biodiversity influences ecosystems and use this information to change our impact on the biosphere. To meet this challenge, we must know where species are, how their distributions change in time and why. However, current methods for determining species distributions are expensive, time intensive and hard to do for multiple species and large geographic regions-​ rendering global trend analysis near infeasible. We therefore need a paradigm shift. In this project we utilize the biotechnology of the fourth industrial revolution (i.e., inexpensive sequencing and computational power) to empirically change how we sample animal and plant biodiversity to solve the infeasibility problem of tracking multiple species distributions on large…

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