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Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)
UMR 7238 CNRS - Sorbonne Université
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CNRS-grand-1200pxl-f40
  • Home
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    • Softwares
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
    • Analytical Genomics
    • Biology of Genomes
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Mathematical Modeling in Biology
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Mathematical Modeling in Biology
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
    • Test-biology
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    • Adaptation, Intégration, Reticulation, Evolution (AIRE)
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    • Biology of Genomes
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    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Mathematical Modeling in Biology
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
    • Telomere & Genome Stability
    • Test-biology
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    • Computational Medicine
    • Epigenetics and RNA Metabolism in Human Diseases
    • Functional Imaging Of Nuclear Architecture (FIONA)
    • Genetic Networks
    • Horizontal Evolution of Algal Lifestyles (HEAL)
    • Mathematical Modeling in Biology
    • Molecular Modeling and Drug Discovery (M2D2)
    • Proteome Diversification in Evolution
    • Statistical Genomics and Biological Physics
    • Synthetic and Systems Biology of Microalgae
    • Systems Engineering and Evolution Dynamics (SEED)
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Publications / Statistical Genomics and Biological Physics

Towards parsimonious generative modeling of RNA families

Calvanese F., Lambert C., Nghe P., Zamponi F., Weigt M. Nucleic Acids Research (2024)

Comments Off on Towards parsimonious generative modeling of RNA families
10 June 2024
Publications / Statistical Genomics and Biological Physics

Generating interacting protein sequences using domain-to-domain translation

Meynard-Piganeau B., Fabbri C., Weigt M., Pagnani A., Feinauer C. Bioinformatics (2023)

Comments Off on Generating interacting protein sequences using domain-to-domain translation
1 July 2023
Publications / Statistical Genomics and Biological Physics

Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems

Ciarella S., Trinquier J., Weigt M., Zamponi F. Machine Learning: Science and Technology (2023)

Comments Off on Machine-learning-assisted Monte Carlo fails at sampling computationally hard problems
1 March 2023
Publications / Statistical Genomics and Biological Physics

TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes

Meynard-Piganeau B., Feinauer C., Weigt M., Walczak A., Mora T. Preprint (2023)

Comments Off on TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes
1 January 2023
Publications / Statistical Genomics and Biological Physics

Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis

Patteson J., Fortinez C., Putz A., Rodriguez-Rivas J., Bryant L., Adhikari K., Weigt M., Schmeing T., Li B. Journal of the American Chemical Society (2022)

Comments Off on Structure and Function of a Dehydrating Condensation Domain in Nonribosomal Peptide Biosynthesis
10 August 2022
Publications / Statistical Genomics and Biological Physics

Modeling Sequence-Space Exploration and Emergence of Epistatic Signals in Protein Evolution

Bisardi M., Rodriguez-Rivas J., Zamponi F., Weigt M. Molecular Biology and Evolution (2022)

Comments Off on Modeling Sequence-Space Exploration and Emergence of Epistatic Signals in Protein Evolution
7 January 2022
Publications / Statistical Genomics and Biological Physics

adabmDCA: adaptive Boltzmann machine learning for biological sequences

Muntoni A., Pagnani A., Weigt M., Zamponi F. BMC Bioinformatics (2021)

Comments Off on adabmDCA: adaptive Boltzmann machine learning for biological sequences
1 December 2021
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