Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity.

Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity. – CQSB

Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)

UMR 7238 CNRS - Sorbonne Universite

Laboratory of Computational, Quantitative and Synthetic Biology (CQSB)

UMR 7238 CNRS - Sorbonne Université

Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity.

Post category:Analytical Genomics / Publications

Chauvot de Beauchêne I., Allain A., Panel N., Laine E., Trouvé A., Dubreuil P., Tchertanov L. PLoS Computational Biology (2014)

Tags: Allain A

Alessandra Carbone

Position: Professor Team: Analytical Genomics E-mail: alessandra DOT carbone AT lip6 DOT fr Tel.Office: +33(0)1 44.27.73.45 Personal Webpage: http://www.ihes.fr/~carbone/ Address: Biologie Computationnelle et Quantitative UMR 7238 CNRS - Sorbonne Université Institut de Biologie Paris Seine Campus Jussieu Bât. C - 4ème étage 4, place Jussieu 75005 Paris, France

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Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity.

Alessandra Carbone

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Alessandra Carbone

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