The CST complex, a new player in DNA repair

Take a look at this CNRS outreach article about our recent publication:https://www.insb.cnrs.fr/fr/cnrsinfo/le-complexe-cst-un-acteur-inattendu-de-la-reparation-de-ladn For more information: Ilioaia O, Dudragne L, Brocas C, Meneu L, Koszul R, Dubrana K, Xu Z. The CST complex mediates a post-resection non-homologous end joining repair pathway and promotes local deletions in Saccharomyces cerevisiae. Cell Genom. 2025 Jul 8:100947. doi: 10.1016/j.xgen.2025.100947. Epub ahead of print. PMID: 40675158.

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PhD position- DinoPlast

The HEAL group is recruiting a PhD position to the project "DinoPlast", under codirection with Thomas Lacour (Phytox, IFREMER Nantes). In a warming world ocean, identifying the molecular effectors of algal primary production is increasingly important for understanding global carbon cycle processes. Dinoflagellates are by far the least understood group of algae from a molecular point of view. They play complex and important roles as phototrophs, mixotrophs, coral symbionts and agents responsible for harmful algal blooms (HABs), but for which there are historically no feasible experimental models. DinoPlast seeks to build metabolic networks for four dinoflagellate species (Amphidinium, Lepidodinium, Karlodinium and Lingualax) as molecular models of the processes that support the dinoflagellate chloroplast, bridging complementary views of translational profiling and physiology with global ocean ecosystems. Key objectives include establishing RiboSeq as a quantification of gene expression for all four species; assessing changes in the expression of plastid-associated metabolism in each species across…

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Biolit Mission

The HEAL group was pleased to participate in the Biolit mission https://biolit.fr/ for the International Day of Global Biodiversity on May 24, 2025. BioLit is a participatory science program on coastal biodiversity, created and supported by Planète Mer. It is run under the scientific responsibility of the Dinard marine station of the Museum National d'Histoire Naturelle (MNHN). It enables everyone to take action to better understand and preserve the biodiversity of the seaside. We spent a day counting algal and mollusc species at the épave de l'OTAN at Octeville, Normandie, France. The best part of the day was apparently the beer at the end :-)

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LeDNA mission

The HEAL group was pleased to participate in the LeDNA mission, organized for the International Day of Global Biodiversity on May 22, 2024 https://environmental-dna.ethz.ch/research/ercledna/global-lake-sampling.html. The global loss and redistribution of biodiversity is a hallmark of the Anthropocene. Our challenge is to generate information about how altered biodiversity influences ecosystems and use this information to change our impact on the biosphere. To meet this challenge, we must know where species are, how their distributions change in time and why. However, current methods for determining species distributions are expensive, time intensive and hard to do for multiple species and large geographic regions-​ rendering global trend analysis near infeasible. We therefore need a paradigm shift. In this project we utilize the biotechnology of the fourth industrial revolution (i.e., inexpensive sequencing and computational power) to empirically change how we sample animal and plant biodiversity to solve the infeasibility problem of tracking multiple species distributions on large…

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MUM&Co

MUM&Co is a bash script that uses Whole Genome Alignment information provided by MUMmer (v3 and v4) to detect structural variations including deletions, insertions, reciprocal translocations and inversions.

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